Friday, September 16, 2011

Are You An Acne Victim ?

 Acne Cures For Adults
 You should start the acne cures for adults lesions before having to regret the loss of tissues (holes) or the excess fibrotic scarring your system creates when it reacts with a strong inflammatory response, for then acne scar treatment ain't going to be easy or quick.

Acne scars are defined either by loss of tissue (ice pick or pitted, indented boxcar scars, rolling acne scars, depressed fibrotic scars) or by the abnormal formation of new thickened tissues (fibrotic, hypertrophic or keloid scars).

Those acne lesions are injuries caused to the cells lining the sebum canals when there is a sudden outflow of sebum to the surface of the skin caused by hormonal imbalances or because of increased pressure on those cells arising from blockage of such outflow by clogged or blocked skin pores.

In fact acne scarring is the outcome when our immune system has to rely just on its own resources to heal acne lesions, for then it acts according to the evolutionary lesson it learned during our evolutionary drift:

All injuries or wounds, scrapes or blisters represent a perilous threat to our survival, not only due to blood loss, but also due to tissue damage or infection from the invasion of micro-organisms and/or foreign bodies such as dirt, splinters and bacteria.

The acne cures for adults healing mechanism that has evolved to react to such threats has two basic characteristics:

First, there is a quick and robust inflammatory response, which sets on the alarms and triggers a cascade of events that begin with a call to action to its fire fighters by the names of lymphocytes, macrophages, neutrophils and so on... to the injured site.

Second, there is a fibrotic "walling-off" response to isolate foreign bodies, and prevent germs from ceasing the opportunity to penetrate at the site of a lesion.

Problem is those firemen arrive inflamed with chemical weapons and can care less if they also liquefy or destroy adjacent skin and lead to abscess formation.  After all they’ve learned, during our evolutionary drift, that intruders at a site of lesion may become a matter of life or death.

Beauty IS NOT a Priority For Our Immune System

To restore the integrity of the skin as quickly as possible, closure of skin lesions and repair of missing skin tissues occur rapidly by an evolutionary mechanism that leads to granulation and fibrosis, and in other more common words: scars.

Now, in normal skin genesis or in skin regeneration without scars, extracellular matrix is formed with the collagen bundles deposited in a basket weave pattern.

By contrast, when granulation tissues form in wound healing, collagen bundles are laid down in parallel between the margins of the skin lesions. The abnormal architecture of the collagen deposition creates tissues of weaker tensile strength and produces the characteristic scars.

Studies of the wound healing process in humans and in animals show, for a fact, that the first 48 hours after a skin lesion are key in determining the scarring outcome. The best outcome is when interventions are made within this window. A possible explanation is that the small number of signaling molecules in the initial cytokine cascade triggered by the skin healing process can have a deep effect on the levels/ratios of inflammatory cells and growth factors recruited to the wound site.

In addition, the recruited cells influence the receptor profiles on the target cells, further affecting the healing response and subsequent scar deposition.

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